Journal: medRxiv

Article Title: Elevated plasma Complement Factor H Regulating Protein 5 is associated with venous thromboembolism and COVID-19 severity

doi: 10.1101/2022.04.20.22274046

Figure Lengend Snippet: Platelet activation was measured by surface expression of ( A ) P-selectin, ( B ) activated GP IIb/IIIa or ( C ) CD63, following treatment of platelet rich plasma with different concentrations of ( i ) adenosine diphosphate (ADP) ( ii ) convulxin or ( iii ) TRAP6, following pre-incubation (10 minutes) with recombinant CFHR5, or PBS control. Each experiment is represented by an individual point and paired experiments connected by a dotted line. *p<0.05 **p<0.01 ***p<0.001 (p for trend bottom right).

Article Snippet: Platelet-rich plasma (PRP) or isolated platelets were incubated with recombinant CFHR5 in PBS (6 μg/ml, 3845-F5, R&D systems) or PBS alone for 10 minutes before treatment with varying concentrations of ADP (1-5 μM), TRAP-6 (3-15 μM) or convluxin (1-6 ng/ml) for 15 minutes.

Techniques: Activation Assay, Expressing, Clinical Proteomics, Incubation, Recombinant, Control

Journal: Cell Reports Medicine

Article Title: Selective apoptosis of tumor-associated platelets boosts the anti-metastatic potency of PD-1 blockade therapy

doi: 10.1016/j.xcrm.2025.101984

Figure Lengend Snippet:

Article Snippet: Mouse SELP (P-Selectin) ELISA Kit , Elabscience , CatE-EL-M0638.

Techniques: Recombinant, Enzyme-linked Immunosorbent Assay, Software, Staining, Modification, Clinical Proteomics, Membrane

Journal: BMC Neuroscience

Article Title: Exploring extracellular vesicle surface markers and microRNA regulation following remote ischemic conditioning in patients with stroke; a randomized-controlled pilot study

doi: 10.1186/s12868-025-00993-1

Figure Lengend Snippet: EV surface marker changes after RIC treatment: The expression of the EV-markers CD62 and MCP-1 is plotted showing the Log 2 fold changes compared to the baseline sample of each patient. The p-value is shown for both the significant changes within RIC group (red) and compared with the miRNA expression changes over time in Sham group (grey). ( a ) CD62 shows an upregulation in RIC treated patients compared to Sham. ( b ) MCP-1 showed no significant changes in between the different timepoints

Article Snippet: CD62 E/P , R & D Systems , BBA1 , BBIG-E(13D5).

Techniques: Marker, Expressing

Journal: BMC Neuroscience

Article Title: Exploring extracellular vesicle surface markers and microRNA regulation following remote ischemic conditioning in patients with stroke; a randomized-controlled pilot study

doi: 10.1186/s12868-025-00993-1

Figure Lengend Snippet: Correlation analysis of significant miRNA measurements (hsa-miR-19b-3p, hsa-miR-30d-5p, hsa-miR-374a-5p, hsa-miR-20a/20b-5p, hsa-miR-24-3p) and CD62/P-selectin. The histograms on the diagonal show the distribution of each variable. The lower triangular panels depict scatter plots with fitted lines, illustrating the linear relationships between pairs of variables. The upper triangular panels display the correlation coefficients, with significance levels indicated by asterisks (* p < 0.05, ** p < 0.01, *** p < 0.001)

Article Snippet: CD62 E/P , R & D Systems , BBA1 , BBIG-E(13D5).

Techniques: